منابع مشابه
Overview of Treatment of IgA Nephropathy
Immunoglobulin A nephropathy (IgAN) is the most commonly encountered primary glomerulonephritis and it usually follows an indolent clinical course. However, hypertensive patients with proteinuria and renal insufficiency at presentation and patients with severe histological involvement are at high risk to develop endsta-ge renal failure. There is no consensus for the treatment of patients with I...
متن کاملOverview of glucose signaling in mesangial cells in diabetic nephropathy.
Clinical studies such as the Diabetes Control and Complications Trial (DCCT) in subjects with type 1 diabetes (1), the UK Prospective Diabetes Study (UKPDS) in subjects with type 2 diabetes (2), and the Kumamoto Study in Japanese subjects with type 2 diabetes (3) clearly link longstanding hyperglycemia to diabetic nephropathy. Furthermore, the regression of glomerular pathologic changes by the ...
متن کاملThe Genetics of IgA Nephropathy: An Overview from China.
BACKGROUND IgA nephropathy (IgAN) is the most common type of primary glomerulonephritis worldwide. Highly variable data for disease prevalence and reports of familial clustering suggest the involvement of genetic factors in IgAN. As China is an area with a high prevalence of IgAN, Chinese scholars have made a considerable effort to reveal the underlying genetic architecture of IgAN. SUMMARY I...
متن کاملOverview of current and alternative therapies for idiopathic membranous nephropathy.
Membranous nephropathy is one of the leading causes of nephrotic syndrome in adults, which is characterized by edema, hypoalbuminemia, hyperlipidemia, lipiduria, and proteinuria. Determination of idiopathic membranous nephropathy (IMN) disease progression risk is important for guiding initial therapy, with immunosuppressive therapy being reserved for high-risk patients. Because IMN may spontane...
متن کاملAn overview of diabetic nephropathy: Epidemiology, pathophysiology and treatment
Article points 1. Diabetic nephropathy is a complication of both type 1 and type 2 diabetes and is associated with other diabetes-related complications. 2. Diabetic nephropathy is characterised by an increased urinary albumin excretion in the absence of other renal diseases. The earliest clinical evidence of nephropathy is the presence of low but abnormal levels of albumin in the urine, which i...
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ژورنال
عنوان ژورنال: Sohag Medical Journal
سال: 2019
ISSN: 1687-8353
DOI: 10.21608/smj.2019.15692.1038